Experience in Clinical Trials

1. Co Principal Investigator for the study of  “ A Pilot Trial of Adjunctive Prednisone     and Mycobacterium W Immunotherapy in Tuberculous Pericarditis(IMPI) “submitted   to Dept.of Science and Technology, Govt of India.  Funding communication awaited.

2. Principal Investigator for the “ A  phase 2 Randomized, double blind, placebo controlled, parallel group, dose response study of PF – 00489791, acute hemodynamic effect in  subjects with primary pulmonary Hypertension”.

3. Principal investigator for a International multi center randomized double blind study to compare the overall mortality in acutely ill medical patients treated with enoxiparin vs placebo in addition to graduated elastic stockings.  

4. Principal investigator of RUBY-1 study,A randomized double blind placebo controlled mlti center parallel group study of safety  tolerability and efficacy of YM150 in combination with standard treatment in secondary prevention of ischemic vascular events in subjects with acute coronary syndromes.   

5. Principal Investigator for H7T-MC-TABY(b) study :A comparison of Prasugrel and clopidogrel in acute coronary syndrome subjects with Unstable angina?Non ST Elevation Myocardial infarction who are medically managed TRIOLOGY ACS study.

6. Principal Investigator for DU 176b-D-U305_HOKUSAI VTE a phase III randomized, double blind ,parallel group,multi-center, multi-nationalstudy for evaluation of efficacy and safety of (LMW)Heparin/Edoxaban versus (LMW)Heparin/Warfarin in subjects with symptomatic deep vein thrombosis and /or pulmonary embolism.

7. Principal Investigator for CANTOS study – “A randomized, double-blind, placebo-controlled, event-driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable-post-MI patients with elevated hsCRP”.

8. Principal Investigator for – “Global Anticoagulant Registry In the FIELD (GARFIELD): Prospective, multicentre, international Registry of male and female patients newly diagnosed with atrial fibrillation.